Peptides like CJC-1295 and Ipamorelin gently stimulate your body to produce its own growth hormone. This approach is more natural and allows your hormone system to stay active, rather than shutting it down like long-term GH injections can. It’s safer, easier to regulate, and better suited for long-term use.

Yes. While peptides may act more gradually than direct GH, they help your body create physiologic GH pulses, which support fat loss, better sleep, improved recovery, and muscle tone — without the risks of GH overexposure. For most healthy adults with age-related GH decline, this is more than enough.

Yes. Peptides don’t force high GH levels; they work with your body’s feedback system to keep things balanced. This greatly reduces the risk of side effects like insulin resistance, fluid retention, or joint pain, which can happen with overuse of GH injections.

No. Peptides like CJC-1295 and Ipamorelin actually support and preserve your pituitary function. In contrast, long-term use of external GH can reduce your body’s natural GH production.

Yes, and many patients do. We usually recommend a short overlap phase to help your pituitary “wake up,” then taper off GH and continue with peptides for long-term maintenance.

Fasting helps your body respond better to the peptides. After you eat, especially carbs or protein, your insulin levels rise — and high insulin can block growth hormone (GH) release. Waiting 2–3 hours after eating gives your body time to lower insulin and create the right conditions for the peptides to trigger a natural GH pulse.

Yes, you can eat after your injection — but it’s best to wait about 20–30 minutes if possible.

This short delay gives the peptides time to stimulate your natural growth hormone (GH) pulse before food raises insulin, which can blunt the GH response. While not mandatory, waiting a little helps maximize the benefits, especially for fat-burning and sleep quality.

Peptides like CJC-1295 and Ipamorelin work by stimulating your own pituitary gland to release growth hormone (GH). If your pituitary is still functioning — even at a lower level due to aging (somatopause) — it will likely respond to this stimulation, just more gently and gradually.

The good news:

• Most healthy adults with age-related GH decline still have a functional pituitary, just a slower one.

• Clinical studies show that even in older adults, GH secretagogues like CJC-1295 can increase GH and IGF-1 levels significantly over time.

• You’ll still be working with your body's natural rhythm, which lowers the risk of hormone suppression or overdose.

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But if your pituitary is truly non-responsive:

• You won’t feel better, and IGF-1 levels won’t rise after 6–8 weeks of consistent peptide use.

• In that case, we can confirm with a blood test and consider other options, like GH replacement (if medically indicated).

What You Can Do:

• Start with peptide therapy at a moderate dose for 6–8 weeks

• Track how you feel: energy, sleep, recovery, and mood

• Check IGF-1 blood levels before and after treatment

Reassurance:

Most people with age-related fatigue, weight gain, or poor sleep do not have a completely non-functioning pituitary — they have a sluggish one, which peptides are designed to gently support and reactivate.