Topical Progesterone for Men 

What you get is Progesterone 1% ( 10 mg / ml ) 

Dosage & Application

• Apply once daily 1-4 click as doctor prescribe, usually in the evening, before bed time 

• Rub into thin-skinned areas for best absorption, such as:

  • Inner forearms

  • Inner thighs

  • Abdomen (below the navel)

 Where Not to Apply

• Avoid applying to genital area  or directly over nipples.

• Do not apply on open wounds, irritated skin, or areas with thick body hair (as it may reduce absorption).

• Avoid areas that will be washed within 1 hour.

Possible Side Effects (Usually Mild and Temporary)

• Mild fatigue or sleepiness, especially if applied in the morning

• Slight changes in mood or libido in the first few weeks

These symptoms are usually mild, and often resolve as your body adjusts. If anything feels uncomfortable, just let us know — we can adjust your dosage or timing as needed.

Half life 

• Progesterone starts to absorb within minutes after application.

• The half-life is 13–17 hours, which supports once-daily dosing.

• Effects are gradual and cumulative, usually noticeable within a few weeks of consistent use.

Contraindications

• A history of hormone-sensitive cancers (such as prostate cancer)

Drug Interactions

• Corticosteroids (e.g. prednisone):
  Progesterone and steroids work through similar pathways in the body. When used together, they may slightly affect adrenal or immune function. This isn’t usually a problem, but your doctor may monitor your progress just to keep everything in balance.

• DHEA:
  DHEA and progesterone are both natural hormones that share the same production pathway. Taking them together is often helpful, but your doctor may fine-tune your dose to make sure you feel your best and avoid minor symptoms like fatigue or mood swings.

• Anticonvulsants (e.g. phenytoin, carbamazepine):
  These medications can speed up how your body breaks down hormones, which may make progesterone slightly less effective. This is nothing to worry about — your doctor will simply adjust the dose if needed so you still get the full benefit.

How to store 

• Room temperature: Store between 15–25°C (59–77°F).

• Avoid heat: Do not store near windows, radiators, or in a car.

• Keep away from direct sunlight: UV light can degrade the hormone.

• Avoid moisture: Do not store in the bathroom.

• Seal tightly: Always close the pump or cap after each use.

When can I see result ?

• Within 3–7 days: Many men report feeling calmer, more emotionally balanced, and notice better sleep quality.

• 2–4 weeks: Improvements in mood stability, reduced irritability, and better synergy with testosterone therapy become more noticeable.

Results vary by individual, but low-dose topical progesterone often provides subtle yet meaningful support within the first few weeks of consistent use.